粘蛋白5B(MUC5B)多克隆抗體
Polyclonal Antibody to Mucin 5 Subtype B (MUC5B)
MUC5-B; MUC9; MG1; Oligomeric Mucus/Gel-Forming; Mucin 5,Subtype B,Tracheobronchial; Cervical mucin; High molecular weight salivary mucin MG1; Sublingual gland mucin
- 編號UPAA684Ra03
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源多抗制備
- 宿主兔
- 效價-
- Ig類型 IgG
- 純化方式抗原特異性親和純化
- 標記物無標記物
- 免疫原 RPA684Ra03-粘蛋白5B(MUC5B)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度500μg/mL
- 且適物種Mus musculus (Mouse，小鼠)
- 應(yīng)用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 308 ¥ 718 ¥ 1026 ¥ 2565 ¥ 10260
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Used in DAB staining on fromalin fixed paraffin- embedded Kidney tissue
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Figure. Western Blot; Sample: Recombinant MUC5B, Rat.
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通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對MUC5B的兔多克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別MUC5B。
用法
Western blotting: 0.5-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPA684Ra02 | 粘蛋白5B(MUC5B)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPA684Ra03 | 粘蛋白5B(MUC5B)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPA684Ra01 | 粘蛋白5B(MUC5B)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA684Ra03 | 粘蛋白5B(MUC5B)多克隆抗體 | WB; IHC; ICC; IP. |
| UPAA684Ra02 | 粘蛋白5B(MUC5B)多克隆抗體 | IHC |
| UPAA684Ra01 | 粘蛋白5B(MUC5B)多克隆抗體 | WB |
| USEA684Ra | 粘蛋白5B(MUC5B)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMA684Ra | 粘蛋白5B(MUC5B)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| UKSA684Ra01 | 粘蛋白5B(MUC5B)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻
| 雜志 | 參考文獻 |
| The Journal of Biological Chemistry | The Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase/Ribosomal S6 Protein Kinase 1 Cascade Phosphorylates cAMP Response Element-binding Protein to Induce MUC5B Gene Expression via D-Prostanoid Receptor Signaling [Jcb: 34199] |
| The Journal of Biological Chemistry | The ERK MAPK/RSK1 cascade phosphorylates CREB to induce MUC5B gene expression via DP1 receptor signaling [Jcb: 247684] |
| Respiratory Researh | Pyocyanin-induced mucin production is associated with redox modification of FOXA2 [PubMed: PMC3765780] |
| Respirology | Secreted mucins and airway bacterial colonization in non-CF bronchiectasis [PubMed: 26172851] |
| American Thoracic Society International Conference Abstracts | Mucin Secretion In Asthmatics With Osmotic Airway Hyperresponsiveness [doi:10.1164] |
| Ann Am Thorac Soc | Airway Mucin 2 Is Decreased in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization [doi:10.1513] |
| Секреторно-экссудативная реакция слизистой носа на воздействие холодного воздуха у больных бронхиальной астмой [10.20538/1682-0363-2017-2-146-158] | |
| Allergy | Th2 cytokines orchestrate the secretion of MUC 5 AC and MUC 5B in IL‐5 positive chronic rhinosinusitis with nasal polyps [Pubmed:29802623] |
| European?Journal of Pharmacology? | Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling [Pubmed:29382534] |
| Japan Society of Immunology & Allergology in Otolaryngology | インフルエンザ菌Phosphorylcholine の表出と中耳ムチンMUC5AC 及びMUC5B 産生への影響 [10.5648:jjiao.36.7] |
| Journal of Investigative?Medicine | The characteristics and clinical significance of mucin levels in bronchoalveolar lavage fluid of patients with interstitial lung disease [Pubmed: 30573494] |
| Mucosal Immunology | ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism [Pubmed: 31278375] |
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