補(bǔ)體成分5(C5)重組蛋白
Recombinant Complement Component 5 (C5)
CPAMD4; C5a anaphylatoxin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
- 編號URPB969Hu02
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位分泌
- 預(yù)測分子量55.2kDa
- 實(shí)際分子量55kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Ser1055~Asn1513 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 95%
- 等電點(diǎn)6.4
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價(jià)格 ¥ 552 ¥ 1380 ¥ 2760 ¥ 8280 ¥ 20700
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過一個(gè)月，-80°C不超過12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
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相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPB969Hu01 | 補(bǔ)體成分5(C5)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UAPB969Hu02 | 補(bǔ)體成分5(C5)活性蛋白 | Cell?culture;?Activity?Assays. |
| URPB969Hu02 | 補(bǔ)體成分5(C5)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAB969Hu01 | 補(bǔ)體成分5(C5)多克隆抗體 | WB; IHC |
| UPAB969Hu02 | 補(bǔ)體成分5(C5)多克隆抗體 | WB; IHC; ICC; IP. |
| ULAB969Hu71 | 補(bǔ)體成分5(C5)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| UMAB969Hu22 | 補(bǔ)體成分5(C5)單克隆抗體 | WB |
| UMAB969Hu21 | 補(bǔ)體成分5(C5)單克隆抗體 | WB |
| USEB969Hu | 補(bǔ)體成分5(C5)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMB969Hu | 補(bǔ)體成分5(C5)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Journal of Clinical Immunology | Complement activation contributes to the injury and outcome of kidney in human anti-glomerular basement membrane disease. [PubMed: 22941511] |
| Journal of Neuroimmunology | Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis [Pubmed:27235358] |
| Cancer Letters | Complement C5a/C5aR pathway potentiates the pathogenesis Q5 of gastric cancer by down-regulating p21 expression [pubmed:29031586] |
| Proteomics?Clinical?Applications | iTRAQ‐Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism [Pubmed:29274201] |
| American journal of physiology. Endocrinology and metabolism | Impaired insulin signaling in the B10.D2-Hc H2 H2-T18/oSnJ mouse model of complement factor 5 (C5) deficiency [Pubmed: 31084499] |
| Proteomics Clinical Applications | Comparative proteomics analysis of serum proteins in gestational diabetes during early and middle stages of pregnancy [Pubmed: 31162828] |
| Aging | C5aR deficiency attenuates the breast cancer development via the p38/p21 axis [Pubmed: 32669478] |
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