腎損傷分子1(Kim1)多克隆抗體
Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)
HAVCR1; TIM1; TIMD1; HAVCR; Hepatitis A Virus Cellular Receptor 1; T Cell Immunoglobulin And Mucin Domain-Containing Protein 1; T-cell immunoglobulin mucin receptor 1
- 編號UPAA785Ra01
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源多抗制備
- 宿主兔
- 效價-
- Ig類型 IgG
- 純化方式抗原特異性親和純化
- 標記物無標記物
- 免疫原 RPA785Ra01-腎損傷分子1(Kim1)重組蛋白
- 緩沖液成份磷酸鹽緩沖液（pH7.4,含有0.02% NaN3和50%甘油）
- 性狀液體
- 濃度0.5mg/mL
- 且適物種-
- 應用IHC
如果抗體需用于流式細胞術，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 308 ¥ 718 ¥ 1026 ¥ 2565 ¥ 10260
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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DAB staining on IHC-P; Samples: Rat Uterus Tissue; Primary Ab: 10μg/ml Rabbit Anti-Rat Kim1 Antibody Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
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DAB staining on IHC-P;
Samples: Rat Kidney Tissue;
Primary Ab: 10μg/ml Rabbit Anti-Rat Kim1 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19) -
DAB staining on IHC-P;
Samples: Rat Testis Tissue;
Primary Ab: 10μg/ml Rabbit Anti-Rat Kim1 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)
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Figure. Western Blot; Sample: Recombinant Kim1, Rat.
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通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對Kim1的兔多克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別Kim1。
用法
Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務
相關產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應用(僅供研究使用，不用于臨床診斷！) |
| UEPA785Ra61 | 腎損傷分子1(Kim1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPA785Ra01 | 腎損傷分子1(Kim1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA785Ra01 | 腎損傷分子1(Kim1)多克隆抗體 | IHC |
| UMAA785Ra21 | 腎損傷分子1(Kim1)單克隆抗體 | IHC |
| USEA785Ra | 腎損傷分子1(Kim1)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| USCA785Ra | 腎損傷分子1(Kim1)檢測試劑盒(化學發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| ULMA785Ra | 腎損傷分子1(Kim1)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| UKSA785Ra01 | 腎損傷分子1(Kim1)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻
| 雜志 | 參考文獻 |
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| Mol Med Rep | Vorinostat protects against calcium oxalate-induced kidney injury in mice [PubMed: 26095064] |
| Pediatr Nephrol | Role of new biomarkers for predicting renal scarring in vesicoureteral reflux: NGAL, KIM-1, and L-FABP [PubMed: 26324091] |
| Journal of Pediatric Urology | Urinary NGAL, KIM-1 and L-FABP concentrations in antenatal hydronephrosis [PubMed: 26096437] |
| Am J Physiol Renal Physiol | Intrarenal Renin-Angiotensin System Mediates Fatty Acid-Induced ER Stress in the Kidney [PubMed: 26672616] |
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| J Clin Lab Anal.? | Kidney Injury Molecule Levels in Type 2 Diabetes Mellitus [Pubmed:27132791] |
| Med Sci Monit. | Protective Effect of Dihydromyricetin Against Lipopolysaccharide-Induced Acute Kidney Injury in a Rat Model [pmc:PMC4754091] |
| Diabetes. | Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis [Pubmed:26822084] |
| Sci Rep. | Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice [Pubmed:27226136] |
| Journal of Applied Life Sciences International | Vitamins C and E Alleviate Nephrotoxicity-induced by Potassium Bromate in Rats [Barakat812016JALSI28698.pdf] |
| Oxidative Medicine and Cellular Longevity | Synergic Effect of α-Mangostin on the Cytotoxicity of Cisplatin in a Cervical Cancer Model. [pubmed:28053694] |
| Molecular Medicine Reports | Attenuation?of?renal?ischemia/reperfusion?injury?by?oleanolic acid?preconditioning?via?itsantioxidant, anti?inflammatory, and anti?apoptotic?activities. [pubmed:27082705] |
| Journal of Agricultural and Food Chemistry | Protective Effects of DHA-PC against Vancomycin-Induced Nephrotoxicity through the Inhibition of Oxidative Stress and Apoptosis in BALB/c Mice [pubmed:29254330] |
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| Nephron - Physiology | Urinary Kidney Injury Molecule-1 but Not Urinary Neutrophil Gelatinase Associated Lipocalin Is Increased after Short Maximal Exercise [10.1159/000481179] |
| Cellular?Physiology and Biochemistry | Gum Acacia Improves Renal Function and Ameliorates Systemic Inflammation, Oxidative and Nitrosative Stress in Streptozotocin-Induced Diabetes in Rats?… [Pubmed:29550811] |
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| Molecules | Effect of Pinocembrin Isolated from Mexican Brown Propolis on Diabetic Nephropathy [Pubmed:29642511] |
| American Journal of Physiology-Regulatory Integrative and Comparative Physiology | Modeling heart failure risk in diabetes and kidney disease: limitations and potential applications of transverse aortic constriction in high-fat-fed mice [Pubmed:29443547] |
| Biological?Trace?Element?Research | Effect of Aqueous Extract of?Glycyrrhiza glabra?on the Biochemical Changes Induced by Cadmium Chloride in Rats [Pubmed: 30251228] |
| Cancer?Research?and?Treatment | A Phage Display-Identified Peptide Selectively Binds to Kidney Injury Molecule-1(KIM-1) and Detects KIM-1-Overexpressing Tumors in vivo [] |
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| Biological?&?Pharmaceutical?Bulletin | UPLC/MS-Based Metabolomics Investigation of the Protective Effect of Hydrogen Gas Inhalation on Mice with Calcium Oxalate-Induced Renal Injury [Pubmed: 30381664] |
| Kidney?and?Blood?Pressure?Research | The Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy [Pubmed: 30504713] |
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| Naunyn-Schmiedeberg's archives of pharmacology | Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascade [Pubmed: 31197431] |
| Egyptian Journal of Zoology | Effect of Cucumis melo var. flexuosus leaves extract on renal oxidative injury and inflammation in diabetic male albino rats [] |
| Environment International | Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixtures [Pubmed: 31639605] |
| Bioscience Reports | page Metabolomics study of fasudil on cisplatin-induced kidney injury [Pubmed: 31670380] |
| life sciences | MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injury [Pubmed: 31790686] |
| Arch Physiol Biochem | Protective effect of saxagliptin against renal ischaemia reperfusion injury in rats [Pubmed: 31979992] |
| clinical science | Delineating a role for the Mitochondrial Permeability Transition Pore in Diabetic Kidney Disease by targeting Cyclophilin D [Pubmed: 31943002] |
| LIFE SCIENCES | Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathway [Pubmed: 32798557] |
| INTERNATIONAL UROLOGY AND NEPHROLOGY | Serum NGAL, KIM-1, IL-18, L-FABP: new biomarkers in the diagnostics of acute kidney injury (AKI) following invasive cardiology procedures [Pubmed: 32557377] |
| Journal of Pediatric Urology | Can Serum Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 Help in Decision Making for Surgery in Antenatally Dedected?… [Pubmed: 33139211] |
| Ratlarda sodyum florid ile olu?turulan toksikasyonda Karvakol'ün b?brekler üzerine etkisi [] | |
| Rationale and design of the intervention in PHOspholamban RElated CArdiomyopathy STudy (i-PHORECAST) [] | |
| Pediatr Int | Early Kidney Injury in Immunoglobulin A Vasculitis: Role of Renal Biomarkers [33423326] |
| J Int Med Res | Value of urinary kidney injury molecule-1 levels in predicting acute kidney injury in very low birth weight preterm infants [33372811] |
| Biomed Res Int | Renal Protective Effect of Beluga Lentil Pretreatment for Ischemia-Reperfusion Injury [33604384] |
| Nutrients | Targeting Methylglyoxal in Diabetic Kidney Disease Using the Mitochondria-Targeted Compound MitoGamide [33922959] |
| J Am Soc Nephrol | Kim-1 Targeted Extracellular Vesicles: A New Therapeutic Platform for RNAi to Treat AKI [34127536] |
| Heliyon | Anti-oxidant impact of Lisinopril and Enalapril against acute kidney injury induced by doxorubicin in male Wistar rats: involvement of kidney injury molecule-1 [33506137] |
| Journal of Pharmacological Sciences | Pentoxifylline treatment alleviates kidney ischemia/reperfusion injury: Novel involvement of galectin-3 and ASK-1/JNK & ERK1/2/NF-|êB/HMGB-1 trajectories [34030796] |
| Int Urol Nephrol | Could urinary kidney injury molecule-1 be a good marker in subclinical acute kidney injury in mild to moderate COVID-19 infection? [34213713] |
| Intensive Care Medicine Experimental | Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental?… [34169407] |
| iscience | Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure [34820603] |
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