腎損傷分子1(Kim1)單克隆抗體
Monoclonal Antibody to Kidney Injury Molecule 1 (Kim1)
HAVCR1; TIM1; TIMD1; HAVCR; Hepatitis A Virus Cellular Receptor 1; T Cell Immunoglobulin And Mucin Domain-Containing Protein 1; T-cell immunoglobulin mucin receptor 1
- 編號(hào)UMAA785Ra21
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱(chēng)，不同的物種。
- 來(lái)源單抗制備
- 宿主小鼠
- 效價(jià)(克隆號(hào))C8
- Ig亞型 IgG1 Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標(biāo)記物無(wú)標(biāo)記物
- 免疫原 RPA785Ra01-腎損傷分子1(Kim1)重組蛋白
- 緩沖液成份磷酸鹽緩沖液（pH7.4,含有0.02% NaN3和50%甘油）
- 性狀液體
- 濃度1mg/mL
- 且適物種-
- 應(yīng)用IHC
如果抗體需用于流式細(xì)胞術(shù)，請(qǐng)參見(jiàn)流式抗體。 - 下載 英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價(jià)格 ¥ 326 ¥ 760 ¥ 1086 ¥ 2715 ¥ 10860
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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DAB staining on IHC-P; Sample: Rat Kidney Tissue; Primary Ab: 20μg/ml Mouse Anti-Rat Kim1 Antibody Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
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DAB staining on IHC-P;
Sample: Rat Testis Tissue;
Primary Ab: 20μg/ml Mouse Anti-Rat Kim1 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
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通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
特異性
該抗體是針對(duì)Kim1的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別Kim1。
用法
Western blotting: 0.01-2μg/mL
Immunohistochemistry: 5-20μg/mL
Immunocytochemistry: 5-20μg/mL
Optimal working dilutions must be determined by end user.
儲(chǔ)存
經(jīng)常使用則4°C保存。-20°C保存不超過(guò)兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
贈(zèng)品
增值服務(wù)
抗體標(biāo)記定制服務(wù)
Protein-A/G純化柱
細(xì)胞和組織染色液
抗體陽(yáng)性對(duì)照品
組織/切片定制服務(wù)
磷酸化抗體定制服務(wù)
免疫印跡(WB)實(shí)驗(yàn)服務(wù)
免疫組織化學(xué)(IHC)實(shí)驗(yàn)服務(wù)
免疫細(xì)胞化學(xué)(ICC)實(shí)驗(yàn)服務(wù)
流式細(xì)胞術(shù)(FCM)實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
免疫熒光(IF)實(shí)驗(yàn)服務(wù)
緩沖液
DAB顯色試劑盒
SABC試劑盒
長(zhǎng)臂生物素標(biāo)記試劑盒
實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| UEPA785Ra61 | 腎損傷分子1(Kim1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPA785Ra01 | 腎損傷分子1(Kim1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA785Ra01 | 腎損傷分子1(Kim1)多克隆抗體 | IHC |
| UMAA785Ra21 | 腎損傷分子1(Kim1)單克隆抗體 | IHC |
| USEA785Ra | 腎損傷分子1(Kim1)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| USCA785Ra | 腎損傷分子1(Kim1)檢測(cè)試劑盒(化學(xué)發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| ULMA785Ra | 腎損傷分子1(Kim1)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| UKSA785Ra01 | 腎損傷分子1(Kim1)檢測(cè)試劑盒DIY材料(酶聯(lián)免疫吸附試驗(yàn)法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
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| Pediatric Research | Urinary Neutrophil Gelatinase-Associated Lipocalin at Birth Predicts Early Renal Function in Very Low Birth Weight Infants [LWW: 10000] |
| Archives of Medical Science | Markers of kidney function in the elderly in relation to the new CKD-EPI formula for estimation of glomerular filtration rate [AMS: source] |
| Nephrology | Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content [PubMed: 23046363] |
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| Journal of Biomarkers | Urinary Measurement of Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 Helps Diagnose Acute Pyelonephritis in a Preclinical Model [Hindawi: 413853] |
| Advances in Life Science and Technology | Kidney injury molecule-1: a urinary biomarker for contrast induced acute kidney injury. [Iiste: Source] |
| Nephrology | Urinary neutrophil gelatinase-associated lipocalin predicts graft loss after acute kidney injury in kidney transplant [Pubmed: 24325180] |
| Nephrology | Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content. [Pubmed: 23046363] |
| BioMed Research International | The Renal Effects of Vanadate Exposure: Potential Biomarkers and Oxidative Stress as a Mechanism of Functional Renal Disorders—Preliminary Studies [Hindawi: 740105] |
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| Diabetes & Vascular Disease Research | Urinary Kim-1 is a sensitive biomarker for the early stage of diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats [Sagepub:Source] |
| 臨床兒科雜志 | 中性粒細(xì)胞明膠酶相關(guān)脂質(zhì)運(yùn)載蛋白、腎損傷分子1和白介素18 在診斷心肺分流術(shù)后急性腎損傷中的意義 [Jcp-Sh:Source] |
| Nephrology (Carlton). | Tubular urinary biomarkers do not identify aetiology of acute kidney injury in kidney transplant recipients [Pubmed:24666430] |
| PLoS One. | Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion [Pubmed:24816434] |
| BMC Nephrology | SYNbiotics Easing Renal failure by improving Gut microbiologY (SYNERGY): a protocol of placebo-controlled randomised cross-over trial [Pubmed:24996842] |
| Pediatric Nephrology | The diagnosis of febrile urinary tract infection in children may be facilitated by urinary biomarkers [Pubmed:25127917] |
| Inflammation.? | Systemic and Flap Inflammatory Response Associates with Thrombosis in Flap Venous Crisis [Pubmed:25448261] |
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| Int J Clin Exp Pathol | Rosiglitazone attenuates renal injury caused by hyperlipidemic pancreatitis [PubMed: 26191125] |
| Int J Clin Exp Pathol | Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice [PubMed: 26045773] |
| Mol Med Rep | Vorinostat protects against calcium oxalate-induced kidney injury in mice [PubMed: 26095064] |
| Pediatr Nephrol | Role of new biomarkers for predicting renal scarring in vesicoureteral reflux: NGAL, KIM-1, and L-FABP [PubMed: 26324091] |
| Journal of Pediatric Urology | Urinary NGAL, KIM-1 and L-FABP concentrations in antenatal hydronephrosis [PubMed: 26096437] |
| Am J Physiol Renal Physiol | Intrarenal Renin-Angiotensin System Mediates Fatty Acid-Induced ER Stress in the Kidney [PubMed: 26672616] |
| Mol Med Rep. | Attenuation of renal ischemia/reperfusion injury by oleanolic acid preconditioning via its antioxidant, anti?inflammatory, and anti?apoptotic activities. [Pubmed:27082705] |
| Nephrol. Dial. Transplant. | Preconditioned suppression of prolyl-hydroxylases attenuates renal injury but increases mortality in septic murine models [Pubmed:26908768] |
| J Clin Lab Anal.? | Kidney Injury Molecule Levels in Type 2 Diabetes Mellitus [Pubmed:27132791] |
| Med Sci Monit. | Protective Effect of Dihydromyricetin Against Lipopolysaccharide-Induced Acute Kidney Injury in a Rat Model [pmc:PMC4754091] |
| Diabetes. | Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis [Pubmed:26822084] |
| Sci Rep. | Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice [Pubmed:27226136] |
| Journal of Applied Life Sciences International | Vitamins C and E Alleviate Nephrotoxicity-induced by Potassium Bromate in Rats [Barakat812016JALSI28698.pdf] |
| Oxidative Medicine and Cellular Longevity | Synergic Effect of α-Mangostin on the Cytotoxicity of Cisplatin in a Cervical Cancer Model. [pubmed:28053694] |
| Molecular Medicine Reports | Attenuation?of?renal?ischemia/reperfusion?injury?by?oleanolic acid?preconditioning?via?itsantioxidant, anti?inflammatory, and anti?apoptotic?activities. [pubmed:27082705] |
| Journal of Agricultural and Food Chemistry | Protective Effects of DHA-PC against Vancomycin-Induced Nephrotoxicity through the Inhibition of Oxidative Stress and Apoptosis in BALB/c Mice [pubmed:29254330] |
| Clin Exp Pharmacol Physiol. | Early urinary biomarkers of renal tubular damage by a high-salt intake independent of blood pressure in normotensive rats. [pubmed:29027259] |
| Nephron - Physiology | Urinary Kidney Injury Molecule-1 but Not Urinary Neutrophil Gelatinase Associated Lipocalin Is Increased after Short Maximal Exercise [10.1159/000481179] |
| Cellular?Physiology and Biochemistry | Gum Acacia Improves Renal Function and Ameliorates Systemic Inflammation, Oxidative and Nitrosative Stress in Streptozotocin-Induced Diabetes in Rats?… [Pubmed:29550811] |
| Frontiers in Pharmacology | Exploring the therapeutic mechanism of Desmodium styracifolium on oxalate crystal-induced kidney injuries using comprehensive approaches based on?… [Pubmed:29950996] |
| Molecules | Effect of Pinocembrin Isolated from Mexican Brown Propolis on Diabetic Nephropathy [Pubmed:29642511] |
| American Journal of Physiology-Regulatory Integrative and Comparative Physiology | Modeling heart failure risk in diabetes and kidney disease: limitations and potential applications of transverse aortic constriction in high-fat-fed mice [Pubmed:29443547] |
| Biological?Trace?Element?Research | Effect of Aqueous Extract of?Glycyrrhiza glabra?on the Biochemical Changes Induced by Cadmium Chloride in Rats [Pubmed: 30251228] |
| Cancer?Research?and?Treatment | A Phage Display-Identified Peptide Selectively Binds to Kidney Injury Molecule-1(KIM-1) and Detects KIM-1-Overexpressing Tumors in vivo [] |
| Archives?of?Medical?Science | Urinary neutrophil gelatinase-associated lipocalin, kidney injury molecule-1, N-acetyl-β-D-glucosaminidase levels and mortality risk in septic patients with?… [Pubmed: 30393493] |
| Biological?&?Pharmaceutical?Bulletin | UPLC/MS-Based Metabolomics Investigation of the Protective Effect of Hydrogen Gas Inhalation on Mice with Calcium Oxalate-Induced Renal Injury [Pubmed: 30381664] |
| Kidney?and?Blood?Pressure?Research | The Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy [Pubmed: 30504713] |
| Clinica?Chimica?Acta | Urine markers of renal tubular injury in idiopathic membranous nephropathy: A cross sectional study [Pubmed: 30684459] |
| BMC?Complementary and Alternative Medicine | Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicine [Pubmed: 30871515] |
| 2.583 | Application of ELISA Technique and Human Microsomes in the Search for 11β-Hydroxysteroid Dehydrogenase Inhibitors [Doi: BioMed Research International] |
| Naunyn-Schmiedeberg's archives of pharmacology | Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascade [Pubmed: 31197431] |
| Egyptian Journal of Zoology | Effect of Cucumis melo var. flexuosus leaves extract on renal oxidative injury and inflammation in diabetic male albino rats [] |
| Environment International | Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixtures [Pubmed: 31639605] |
| Bioscience Reports | page Metabolomics study of fasudil on cisplatin-induced kidney injury [Pubmed: 31670380] |
| life sciences | MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injury [Pubmed: 31790686] |
| Arch Physiol Biochem | Protective effect of saxagliptin against renal ischaemia reperfusion injury in rats [Pubmed: 31979992] |
| clinical science | Delineating a role for the Mitochondrial Permeability Transition Pore in Diabetic Kidney Disease by targeting Cyclophilin D [Pubmed: 31943002] |
| LIFE SCIENCES | Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathway [Pubmed: 32798557] |
| INTERNATIONAL UROLOGY AND NEPHROLOGY | Serum NGAL, KIM-1, IL-18, L-FABP: new biomarkers in the diagnostics of acute kidney injury (AKI) following invasive cardiology procedures [Pubmed: 32557377] |
| Journal of Pediatric Urology | Can Serum Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 Help in Decision Making for Surgery in Antenatally Dedected?… [Pubmed: 33139211] |
| Ratlarda sodyum florid ile olu?turulan toksikasyonda Karvakol'ün b?brekler üzerine etkisi [] | |
| Rationale and design of the intervention in PHOspholamban RElated CArdiomyopathy STudy (i-PHORECAST) [] | |
| Pediatr Int | Early Kidney Injury in Immunoglobulin A Vasculitis: Role of Renal Biomarkers [33423326] |
| J Int Med Res | Value of urinary kidney injury molecule-1 levels in predicting acute kidney injury in very low birth weight preterm infants [33372811] |
| Biomed Res Int | Renal Protective Effect of Beluga Lentil Pretreatment for Ischemia-Reperfusion Injury [33604384] |
| Nutrients | Targeting Methylglyoxal in Diabetic Kidney Disease Using the Mitochondria-Targeted Compound MitoGamide [33922959] |
| J Am Soc Nephrol | Kim-1 Targeted Extracellular Vesicles: A New Therapeutic Platform for RNAi to Treat AKI [34127536] |
| Heliyon | Anti-oxidant impact of Lisinopril and Enalapril against acute kidney injury induced by doxorubicin in male Wistar rats: involvement of kidney injury molecule-1 [33506137] |
| Journal of Pharmacological Sciences | Pentoxifylline treatment alleviates kidney ischemia/reperfusion injury: Novel involvement of galectin-3 and ASK-1/JNK & ERK1/2/NF-|êB/HMGB-1 trajectories [34030796] |
| Int Urol Nephrol | Could urinary kidney injury molecule-1 be a good marker in subclinical acute kidney injury in mild to moderate COVID-19 infection? [34213713] |
| Intensive Care Medicine Experimental | Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental?… [34169407] |
| iscience | Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure [34820603] |
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